A number of people have suggested that it would be of great benefit to scientists who are starting to develop a detailed interest in the question of what the inside of cells is really like, and in the (probably) related questions of the organisation of metabolic channeling and the control of metabolic fluxes, to have access to a short bibliography that would serve to outline most of the issues, and to summarise the evidence that leads many to believe that the inside of a cell is far more organised than textbooks usually credit. There follows a short and necessarily eclectic selection that we believe will be helpful. * indicates what might be considered the first 5.
*Welch, G. R. (1977). On the role of organized multienzyme systems in cellular metabolism: a general synthesis. Prog. Biophys. Molec. Biol. 32, 103-191.
Srere, P.A. & Estabrook, R.W. (eds) Microenvironments and metabolic compartmentation. Academic Press, New York, 1978.
*Clegg, J. S. (1984). Properties and metabolism of the aqueous cytoplasm and its boundaries. Am. J. Physiol. 246, R133-R151
[various] (1984) J.Cell Biol. 99 (No.1, part 2) pp 3S-248S (S for supplement) "The Cytoplasmic Matrix and Cellular Function".
Welch, G.R. (ed.) Organized Multi-enzyme Systems: Catalytic Properties. Academic Press, New York, 1985.
Welch, G.R. & Clegg, J.S. (eds). The Organisation of Cell Metabolism, Plenum Press, New York, 1986.
Welch, G.R. (ed) The Fluctuating Enzyme, Wiley, New York, 1986.
*Srere, P. A. (1987). Complexes of sequential metabolic enzymes. Annu. Rev. Biochem. 56, 21- 56.
Westerhoff, H.V. & van Dam, K. Thermodynamics and Control of Biological Free-energy Transduction. Amsterdam: Elsevier, 1987.
Jones, D.P. (ed.), Microcompartmentation. CRC Press, Boca Ration, FL, 1988.
Srere, P., Jones, M.E. & Mathews, C. (eds) Structural and organizational aspects of metabolic regulation, UCLA Symposia on Molecular and Cellular Biology, New Series, Vol 134, Alan R. Liss, New York, 1990.
*Cornish-Bowden, A. & Cárdenas, M.L. Control of metabolic processes. NATO ASI Series Vol 190. Plenum Press, New York, 1990.
Ovádi, J. (1991). Physiological significance of metabolic channelling. J. Theoret. Biol. 152, 1-22 (and some, but by no means all, of the papers in this special issue of JTB).
Stadtman, E.R. & Chock, P.B. (eds) From metabolite to metabolism to metabolon. Current Topics in Cellular Regulation Vol 33. Academic Press, New York, 1992.
Brindle, K. (ed.) Enzymology in vivo (Adv. Mol. Cell. Biol. 11) JAI Press, London, 1995.
Kacser, H., Burns, J.A. & Fell, D.A. (1995) The control of flux. Biochem. Soc. Trans. 23, 341- 366
*Ovádi, J. Cell architecture and metabolic channeling. Springer-Verlag, New York, 1995.
Fell, D.A. Understanding metabolic control. Portland Press, London, 1996.
Heinrich, R. & Schuster, S. (1996) The Regulation of Cellular Systems. Chapman & Hall, New York.
Cohen NS. (1996) Intracellular localization of the mRNAs of argininosuccinate synthetase and argininosuccinate lyase around liver mitochondria, visualized by high-resolution in situ reverse transcription-polymerase chain reaction. J Cell Biochem.61:81-96.
Brindle KM, Fulton SM, Gillham H, Williams SP. (1997) Studies of metabolic control using NMR and molecular genetics. J Mol Recognit.10:182-7.
Stapulionis R, Kolli S, Deutscher MP. (1997) Efficient mammalian protein synthesis requires an intact F-actin system. J Biol Chem.272:24980-6.
*Oliver SG, Winson MK, Kell DB, Baganz F. (1998) Systematic functional analysis of the yeast genome. Trends Biotechnol.16:373-8.
Guadagno TM, Ferrell JE Jr. (1998) Requirement for MAPK activation for normal mitotic progression in Xenopus egg extracts. Science.282:1312-5.
Bray D, Levin MD, Morton-Firth CJ. (1998) Receptor clustering as a cellular mechanism to control sensitivity. Nature 393:85-8.
Haggie PM, Brindle KM. (1999) Mitochondrial citrate synthase is immobilized in vivo. J Biol Chem. 12;274:3941-5
Burbulis IE, Winkel-Shirley B. (1999) Interactions among enzymes of the Arabidopsis flavonoid biosynthetic pathway. Proc Natl Acad Sci U S A.96:12929-34.
Den Blaauwen T, Buddelmeijer N, Aarsman ME, Hameete CM, Nanninga N. (1999) Timing of FtsZ assembly in Escherichia coli. J Bacteriol.18: 5167-75.
Jensen PR, Van Der Weijden CC, Jensen LB, Westerhoff HV, Snoep JL. (1999) Extensive regulation compromises the extent to which DNA gyrase controls DNA supercoiling and growth rate of Escherichia coli. Eur J Biochem. 266:865-77.
van der Vlag J, den Blaauwen JL, Sewalt RG, van Driel R, Otte AP.(2000) Transcriptional repression mediated by polycomb group proteins and other chromatin-associated repressors is selectively blocked by insulators. J Biol Chem. 275:697-704.
Liliom K, Wagner G, Pacz A, Cascante M, Kovacs J, Ovadi J. (2000) Organization-dependent effects of toxic bivalent ions Microtubule assembly and glycolysis. Eur J Biochem. 2000 267:4731-4739.
*Westerhoff, H.V. (2000) Live perspectives of biochemistry. The Biochemist 22, 43-47.
Srere PA. Macromolecular interactions: tracing the roots. (2000) Trends Biochem Sci. 25:150-3.
*Ovadi J, Srere PA. (2000) Macromolecular compartmentation and channeling. Int Rev Cytol. 192: 255-80
*Cornish-Bowden, A. & Cárdenas, M.L. (2000) Technological and Medical Implications of Metabolic Control Analysis. Kluwer Academic Publisher, Dordrecht, The Netherlands.
Hofmeyr J.-H. S., Rohwer J.M. & Snoep J.L. (2000) BTK 2000. Animating the Cellular Map. Stellenbosch University Press, RSA
BioComplexity; from dead molecules to live cells, a new journal starting 2001, Kluwer Academic Publisher, Dordrecht, NL, EU (http://www.bio.vu.nl/grc2000/biocomplexity.html).
Suggestions for amendments to the canon are welcome, but there is a rule that says that you should not suggest your own publications!
This bibiography was developed by Douglas Kell and Pedro Mendes and updated by Hans V. Westerhoff