Computer program GRANK is made available to the scientific community free of charge in the interest of scientific progress. Ownership of the program and associated documentation, however, remains with the author to which all queries should be addressed:
Dr. W.P.H. de Boer
Vrije Universiteit medical centre, Dept. Medical Oncology, BR232
De Boelelaan 1117
NL-1081 HV AMSTERDAM, The Netherlands
Email: WPH.deBoer@VUmc.nl
GRANK has been designed to identify distinct sets of genes with similar expression patterns across DNA micro-arrays. Genes are clustered using rank correlation to ensure that the genes selected are really correlated, that is, to a significance level chosen. Clusters will be fairly small: they comprise all genes, including those of small variance, which are positively or negatively correlated. The search for clusters continues until there are no least-correlated genes left with the clusters already found.
IMPORTANT – READ CAREFULLY: By copying, installing or otherwise using computer Program GRANK and associated Documentation, User agrees to be bound by the terms and conditions of this GRANK End-User License Agreement (“Agreement”).
1. DEFINED TERMS. For purposes of this Agreement: (a) “Licensor” means W.P.H. de Boer, voluntary research associate at the VU medical centre (“VUmc”) in Amsterdam, the Netherlands; (b) “Program” means computer program GRANK; (c) “Documentation” means the user manual associated with the Program; (d) “User” means the user of the Program and associated Documentation; and (e) “VU” means the Vrije Universiteit in Amsterdam, the Netherlands.
2. GRANT OF LICENSE. Licensor hereby grants User free of charge a non-exclusive, transferable, perpetual license to use the Program in machine-readable form together with associated Documentation subject to the terms and conditions set forth in this Agreement.
3. RESTRICTIONS. User may not de-compile or disassemble the Program. User may not rent, lease or otherwise merchandize the Program.
4. COPYRIGHT. User understands and agrees that Licensor is not selling or transferring in whole or in part any title to Program and associated Documentation. User may permanently transfer all User´s rights under this Agreement, provided the recipient agrees to the terms of this Agreement.
5. NO WARRANTY. Licensor expressly disclaims any warranty for the Program. The Program and any related Documentation is provided “as is” without warranty of any kind, either expressed or implied. The entire risk arising out of use or performance of the Program remains with the User.
6. LIMITATION OF LIABILITY. In no event will Licensor, VU or VUmc be liable to User for damages, including any general, special, incidental, or consequential damages arising out of the use of the Program.
7. This Agreement shall be exclusively interpreted in accordance with and governed by the Netherlands’ Dutch law, in particular the Copyright Act (Auteurswet).