The Synthesizing Unit as model for the stoichiometric fusion and branching of metabolic fluxes
Kooijman, S. A. L. M. 1998.
The Synthesizing Unit as model for the stoichiometric fusion and branching of metabolic fluxes.
Biophys. Chem. 73: 179 - 188
The Synthesizing Unit SU binds given numbers of substrate molecules of
several types of substrate to produce a product molecule or set of
product molecules. Irreversible binding results in relatively simple
and explicit expressions for the rate of product formation. Reversible
binding can be implemented with relative ease in the carrier-SU
complex, where the products of a set of carriers a special type of SU
serve as substrate for an SU or set of SUs. A simple and parameter
sparse approximation is presented for the production rate of a
generalized compound, i.e. a rich mixture of compounds that does not
change in composition. An analysis of Droop s data on the growth of a
haptophyte on phosphate and vitamin B reserves illustrates the
application of SUs.
- page 182, the formula on line 2 in the paragraph after eq.2 should
read t^j/j! and not n^j/j!.
- page 184, paragraph 3, line 5, there is a dot missing over the p.