Lecture: concluding remarks DEB symposium: 30 years of research on metabolic organisation Speaker: Bas Kooijman Date: 2009/04/22 Location: Ifremer Brest Advanced research calls for a holistic and fundamental approach that needs quantitative theory and theory-inspired experimentation. This requires far more knowledge than any single individual can possibly acquire. For the use of technical equipment (including e.g. computers) we happily accept that we need to know how it works, not how it is constructed. For models, however, many researchers still seem reluctant to use models they don't fully understand in technical detail. This limits the choice to unrealistically simple models that do not meet the criteria for successfully guiding further research. During the last three days, we demonstrated to be able to look beyond these limitations met by individually working scientists, and choose for multidisciplinary collaboration to solve problems that matter. Although this extends our combined capabilities substantially, efficient collaboration comes with its own need for skills. Multidisciplinary research not only requires a carefully chosen composition of the research group in relation to the scientific problem to be solved, but also needs a sufficient overlap in knowledge of team members to allow for productive knowledge exchange. This requires a substantial time and effort investment for all participants in collaboration at a moment when the profits are not fully clear yet. It is only natural that this investment into future success will continue to be evaluated critically. This symposium is the first that is fully devoted to DEB research. It is very satisfying for me to have solid confirmation that 30 years of focused research by a group of varying composition did set a train into motion that will be hard to stop. The reason is in the scientific successes that have been obtained to far. To my judgement, this effort was not only pleasing, but also well-spend. So it provides motivation to proceed along the chosen path. The symposium is a pivot for the further organisation of networking and future collaboration. The near future will reveal its effectiveness in this respect. The DEB tele courses have proven to be effective in motivating young scientists to a fundamental approach to metabolic organisation. Most present DEB research and activity, such as the AQUAdeb group, an increasing number of double doctorates and the special issues of the Journal of Sea Research, originated from these courses. The courses helped me to organise, optimise and maintain the course documentation, the DEB-book and its software support DEBtool; the upcoming third edition is a new step forward, in this respect. I see the link between the course and the symposium as an excellent opportunity to merge education with research and to give course participants a rapid and effective start in mastering the art of abstract conceptual thinking, which is typical for DEB research, and to find their best way through the rapidly extending network. We need to further develop this and possibly extend the course part prior to the symposium, next time in 2011 in Lisbon. We all can be very happy that Tiago and Tania's group offered to take the lead to organise this symposium; their young and dynamic group is developing a firm scientific basis that will power the developments in DEB research. Tomorrow we will have scientific discussions about exciting research topics, some of them related to the DEB theme issue of the Philosophical Transactions of the Royal Society 2010. Needless to say that everybody is warmly invited to partake in these post-symposium discussions. After the summer, in Sept/Oct we continue with the second part of the DEB tele course 2009, which we run 3 parallel programs: "individuals in depth", "population and ecosystem dynamics" and "effects of toxicants". I hope and expect that this symposium provided the motivation to invest the required time and effort these challenging topics need. I want to close this symposium with thanking the organising committee, and especially Marianne Alunno-Bruscia, for the great job they did. I know it is a lot of work and we can only be deeply grateful for it. I also want to thank Ifremer for the financial support they have given so far, both for the symposium and for the activities of the AQUAdeb group, demonstrating their confidence in our enterprise. We did our best to live up to our promises, and we hope to meet satisfaction about our achievements.