Workvisit to Dina Lika, Iraklion  2010/05/12

S.A.L.M. Kooijman
Dept Theoretical Biology, Vrije Universiteit, Amsterdam 
bas@bio.vu.nl; http://www.bio.vu.nl/thb/

Applications of Dynamic Energy Budget (DEB) theory

DEB theory is about the uptake and use of substrates by all organisms (micro-organiosms, animals, plants), based on first principles in chemistry, physics & biology.

I will illustrate the following applications of the standard DEB model:

- reconstruction of food-density and temperature trajectories 
  in the environment from data on
  = growth (using birds)
  = reproduction (using daphnia)
  = otoliths (of fish)
- identification of mode of action of toxicants and quantification of effects
- prediction of tumour growth as affected by caloric restriction
- optimisation of bio-production
  = yield in micro-organisms
  = prediction of spawing in pacific oysters