The innovations by Dynamic Energy Budget theory to understand metabolic organisation S.A.L.M. Kooijman Dept Theoretical Biology, Vrije Universiteit, Amsterdam bas@bio.vu.nl; http://www.bio.vu.nl/thb/ Ifremer Nantes 2005/04/22/09:30-10:15 Metabolic organization of individual organisms seems to follow simple quantitative rules that can be understood from basic physical chemical principles. These rules quantify how individuals acquire and utilize energy and nutrients, while cycling through their life stages. Dynamic Energy Budget (DEB) theory identifies the most basic rules, and links them together in a consistent framework. The DEB theory applies to all species of organisms (unicellular as well as multicellular ones) and links various levels of biological organization; many popular empirical models turn out to be special cases of the standard DEB model, or very close numerical approximations. The lecture will introduce the theory with a discussion of some key-issues: - A comparison of DEB models with Static Energy Budget Models (which are basic to the Scope for Growth concept) and with production models. - The dynamic interactions between surfaces and volumes at the control of body size. - Respiration patterns and product formation. - Body size scaling relationships with a discussion on "popular" explantions for the scaling of metabolic rates. A general introductory paper to the DEB theory can be found at http://www.bio.vu.nl/thb/research/bib/Kooy2001.html