Dr K. Krab

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e-mail: klaas.krab@falw.vu.nl

Room M254
Tel.: 020 5987168
Fax.: 020 5987229

full address:
Dr K. Krab
Department of Molecular Cell Physiology
IMC
Faculty of Earth and Lifesciences
Vrije Universiteit
De Boelelaan 1085
1081 HV Amsterdam (The Netherlands)

Research:

   research groups:

• Coordination of research group Entering the living cell
• Participation in research group Cellular Bioinformatics

Research interests (2011):

• Mathematics and computation for the system biology of cells and mitochondria
• Relation between fatty acid and sugar metabolism in the context of diabetes and obesity
• Identification and characterisation of environmental effects at the molecular level

Teaching:

• bachelor courses
  • Wiskunde (Mathematics) - coordinator
  • Moleculaire Celbiology (Molecular Cell Biology) - coordinator
    
    
  Goodies:
  
  
  • An Excel file with a kinetic model for cytochrome c oxidase (Krab K, Kempe H, Wikström M., Biochim Biophys Acta. 2011 Mar;1807(3):348-58)
    Download oxidase_KKM_2011
    
  
  
  • An Excel file with the oxidase model that includes calculation of control coefficients
    Download oxidase_KKM_2011 control
  
  
  • A full version (including non-steady-state kinetics) of the oxidase model can be found at:
    http://www.jjj.bio.vu.nl/
  
  
  • An Excel file to calculate the free energy change of ATP synthesis ("phosphate potential") at different temperatures (Krab & Van Wezel, Biochim. Biophys. Acta 1098 (1992) 172 - 176).
    Download Pipo_2011